Modafinil is a new generation stimulant, used to control and regulate the process of person waking without prejudice to sleep, which is so necessary in our modern lifestyle. In the late 70s of the last century French pharmaceutical company “Lafon Group” synthesized Modafinil substance. But only in December 1998, Modafinil production and use has been allowed by the American FDA under the brand name Provigil.
Modafinil is an agonist of adrenergic alpha-1, which reinforces dopamine selection in the CNS, but also enhances the selection of GABA (gamma -amino-butyric acid). Modafinil, known as Alertec, Provigil, Modalert, is approved in many countries all over the world, as number one remedy for the treatment of uncontrolled narcolepsy, seizures daytime sleepiness and somatic neurological disorders.
What are the benefits of Modafinil?
- inhibits the desire to sleep
- increases natural durability
- perfects the memory
- refines visual intelligence and other mental activity parameters.
According to the manufacturer, Modafinil pharmacological profile has nothing to do with amphetamines, methylphenidate (Ritalin) and cocaine. The uniqueness of Modafinil is in its ability to act alone if necessary, as well as, in the absence of adverse reactions (anxiety, agitation, insomnia, bighead) which are common and normal for other prescribed stimulants.
Modafinil is not addictive, doesn’t cause euphoria, has little effect on blood pressure and reduces nervous system peripheral stimulation. In the course of the long absence of sleep, patients are prescribed to take Modafinil in moderate doses. During medical trials, it was proved that the drug has a very high level of safety and tolerability.
Other indications to take Modafinil are proved by science and patients:
- Depression (Read article about Modafinil for Depression)
- Alzheimer’s disease
- Attention deficit disorder
- Postanesthesia intoxication
- Age-related memory impairment
- Circadian rhythm disturbance
- Idiopathic hypersomnia
- Multiple sclerosis, caused by fatigue
Modafinil and army: Soldiers’ experience
Modafinil is used in many armies of the world, in the Air Force and the regular army of the United States, the security services, military intelligence units, etc. as the drug, enhancing performance and attention of pilots, soldiers and operatives combat units.
The drug from amphetamine group Dexedrine, which has been used earlier in same cases, is marked significant number of side effects: anxiety, a sense of powerlessness, tremmor, anger. Military operations in Afghanistan and Iraq have proved efficacy and safety of Modafinil in soldiers. All of them claimed about good physical and mental operation during 40 hours without sleep.